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International Research Journal of Pharmacy and Pharmacology

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Maria Koziolek

Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Greece


  • Review Article   
    A Review on the effectiveness of combination therapy of drugs
    Author(s): Maria Koziolek*

    Multidrug resistance (MDR) has long been a major obstacle in the treatment of malignant tumors. Combination therapy provides a viable and promising strategy to overcome MDR. This article discusses the advantages of nano-based combination therapy and proposes a 3R delivery principle (right place, right time, and right dose) as a reference for development of cancer nanomedicine containing drug combinations. The article also reviews the strategies of nano-based codelivery, with emphasis on the techniques designed to overcome chemoresistance, enhance drug targeting delivery, and reduce immunosuppression... View More»
    DOI: 10.14303/2251-0176.2023.71

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