International Research Journals

Jordan Gregg

Department of Medical and Health, College of William and Mary’s Integrated Science Centre, Williamsburg, Virginia, USA


  • Research Article   
    The order in which antibiotics are administered affects the fitness costs of adherent-invasive E. coli (AIEC) strains
    Author(s): Jordan Gregg*

    AIEC-LF82 is a strain of bacteria that is surmised to have a role in causing IBD and Crohn’s disease by activating pro-inflammatory gene expression in organisms. Using antibiotics via combination therapy has been a technique used in clinical settings in an attempt to treat the strains, however, the attempts have not been that effective nor efficient in terms of completely halting the growth and colonization of AIEC to treat IBD and Crohn's disease patients. Research has shown that regarding hindering or preventing the colonization bacterial colonies, sequential therapy tends to be more effective and time-efficient than combination therapy, with fewer adverse effects. To test if this is also the case with the AIEC-LF82 strain of bacteria, I first tested AIEC’s response to combination therapy using the Penicillin-Streptomycin, Kanamycin-Chloramphenicol, antimicrobial pep.. View More»

    Abstract PDF