International Research Journals
Reach Us +44 330 818 7254

International Research Journal of Engineering Science, Technology and Innovation

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

David Ghosh

Department of Civil Engineering, Australia


  • Review Article   
    Using an Active Complementary Metal-Oxide-Semiconductor Biosensor Array with Integrated Sensor Electronics, Multiplexed Electrochemical DNA Detection in Real Time
    Author(s): David Ghosh*

    However, new electrochemical detection methods are emerging that may make it possible to design portable devices for point-of-care applications without the need for physically bulky optical instrumentation. Multiplexed electrochemical detection, in contrast to fluorescence detection, which can work well with a passive substrate, requires an electronically active substrate to analyze each array site. Multiplexed electrochemical detection makes use of integrated electronic instrumentation to further reduce platform size and get rid of electromagnetic interference that can come from bringing non-amplified signals off the chip. For the purpose of performing quantitative DNA hybridization detection on chip using targets conjugated with redox labels, we present an active electrochemical biosensor array constructed using standard complementary metal-oxide-semiconductor (CMOS) technology. On .. View More»
    DOI: 10.14303/2315-5663.2023.91

    Abstract HTML PDF