International Research Journals

Shilu Singh

Department of Neurosurgery, University of Airlangga, Indonesia


  • Mini Review   
    Pediatric Brain Tumors and Models of Pioneering
    Author(s): Shilu Singh*

    Brain and other central nervous system tumours are the second most frequent kinds of cancer among children and adolescents in the United States, after only leukaemias in incidence. Brain cancer continues to be the primary cause of mortality in children despite major advancements in detection and treatment options. It is clear that there is a need to enhance these patients' survival rates and streamline the therapy approaches. Preclinical models are essential for that goal. Pediatric brain tumour research employs a variety of models, including genetically modified mouse models, patient-derived xenografts and cell lines, and more recent models that make use of cutting-edge technologies like genome editing and organoids. Researchers from the Children's Brain Tumor Network and others have conducted significant research that has discovered multiomic landscapes. Of diverse children's br.. View More»
    DOI: 10.14303/irjbcs.2023.23

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