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Quercetin Supplementation and metabolic disturbances in non- | 71967
International Research Journals

Educational Research

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Quercetin Supplementation and metabolic disturbances in non-alcoholic fatty liver disease (NAFLD): A randomized, double-blind, placebo-controlled pilot study

Abstract

Mahboobe Hosseinikia

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease which had become a public health concern, and its growing prevalence has been reported between 2.8%-43.8% in Iran. Since oxidative stress plays a crucial role in pathogenesis of NAFLD, antioxidant compounds such as quercetin could ameliorate the sideeffect of oxidative stress. The aim of the current study was to assess the effect of quercetin on lipid profile, liver enzymes, and inflammatory indices in NAFLD patients. In a randomized, double-blind, placebo-controlled trial conducted as a pilot study, 78 patients with NAFLD were supplemented twice daily (500 mg) for 12 wk with either a quercetin or a placebo capsule

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