+44 3308180992 Research Article
Synergistic Antibacterial Effects of Melia azedarach and Psidium guajava Leaf Extract against Selected Standard and Clinical Isolated Pathogenic Bacteria
Author(s): Moges Demes*, Nega Berhane and Aragaw Zemene
Antibiotic resistance, which can be caused by antibiotic-resistant bacteria, is an emerging global public problem that poses a serious human health problem. Medicinal plants are considered one of the most important alternatives for producing antibiotics used to combat antibiotic resistant bacteria. Therefore, the main objective of this study was to evaluate the synergistic antibacterial effects of Psidium guajava and Melia azedarach against selected clinically and standard pathogenic bacteria. Plant leaves were collected from University of Gondar, Tewodros Campus, air-dried at room temperature, powdered, soaked in methanol, ethanol and chloroform solvents in separate flasks and shaken on a rotary shaker (150 rpm) for 3 days. Antibacterial efficacy was tested individually and in combination against three clinically isolated and standard bacterial species, i.e., S. aureus (ATCC 25923), .. View More»