Prevalence and antimicrobial suseptibility of asymptomatic s | 17719
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International Research Journal of Microbiology

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Prevalence and antimicrobial suseptibility of asymptomatic significant bacteriuria among new antenatal enrollees in Southwest Nigeria


Ade-Ojo IP, Oluyege AO, Adegun PT, Akintayo AA, Aduloju OP, Olofinbiyi BA

Asymptomatic Bacteriuria (ASB) is a common extraintestinal infection with a high prevalence in pregnancy. It portends adverse maternal and fetal outcome if unrecognised and untreated. The aim of this study was to determine the prevalence of ASB, profile and antibiotic susceptibility of isolated uropathogens. This prospective study was carried out between 1st of March 2012 and 31st of January, 2013 among newly enrolled apparently healthy pregnant women who met the inclusion criteria. Clean catch mid-stream urine samples were collected and processed using standard microbiological techniques. We found a prevalence rate of 10.5% significant bacteriuria in pregnancy. Majority (72.4%) were between 25-34 years (30.25±4.58), nulliparous (40.4%) and well educated (83%) women. 51.1% were between 26-30 weeks gestation (25.81±6.01). Eschericia coli (44.7%) followed by Staphylococcus aureus(25.5%) were the commonest bacteria. All uropathogens isolated were resistant to the commonly prescribed antibiotics; cefuroxime (0%) and ceftriazone (0.6%) but susceptible to cefotaxime (87%) and ceftaxidime (81%). Quinolones (Ofloxacine-100% and Ciprofloxacine-89%) were the most susceptible antibiotics. We found that there has been no significant change in the prevalence of ASB in the recent years. Guideline to prevent indiscriminate use of antibiotics is needed to prevent the resistance observed in this study. Keywords: Prevalence, Asymptomatic Bacteriuria, Pregnancy

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