Preliminary phytochemical investigation and antimicrobial e | 16932
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International Research Journal of Biochemistry and Bioinformatics

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Preliminary phytochemical investigation and antimicrobial evaluation of roots, stem-bark and leaves extracts of Diospyros mespiliformis


M. H. Shagal, D. Kubmarawa, and H. Alim

The roots, stem-bark and leaves of Diospyros mespiliformis from Ebanaceae family which is used as herbal remedies for the cure of many ailments by natives in northern part of Nigeria were studied. the Ethanol and water extracts of the afore mentioned parts of the plant were subjected to phytochemical screening and antimicrobial activity against Shigella sp, Salmonella typhii, Escherichia coli, Streptococcus sp, Staphylococcus aureus and Klebsella pneumonia. From the tests carried out, the result revealed the presence of saponins, tannins,volatile oils, alkaloids and phenols in both the leaves extract of the plant. The antimicrobial activity revealed that both the extracts of the plant parts were active against Shigella sp, Escherichia coli, and Streptococcus sp. This supports the claims of efficacy reported in fork use of the plant in the treatment of disease caused by some pathogens and if further purified can be used to source novel antibiotics.

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