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International Research Journal of Pharmacy and Pharmacology

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Pharmacokinetics: The Engine Behind Drug Development and Optimization

Abstract

Anita Verma*

Pharmacokinetics (PK) examines the absorption, distribution, metabolism, and excretion (ADME) of drugs within the human body. It provides essential insights for designing dosage regimens, predicting drug interactions, and ensuring patient safety. Modern drug development integrates PK studies early in the research process to optimize bioavailability, minimize toxicity, and improve therapeutic efficacy. Understanding PK parameters like half-life, clearance, and volume of distribution is critical for both preclinical and clinical stages. This article outlines the role of pharmacokinetics in drug development, its analytical methods, and its contribution to personalized medicine.

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