Ebesunun MO and Adedipe O
Adherence to drug regimen in diabetes mellitus has been observed to have contributed significantly to poor management in many populations. This study was designed to assess the relationship of HbA1c to Morisky score in type II diabetes in high income group. Sixty subjects consisting of 30 type 2 diabetes mellitus patients. age range (38-60 years) and 30 age and sex marched non -diabetes controls (40-59 years) were selected for this study. Anthropometric and biochemical parameters were determined using standard procedures. Results showed significant increases in plasma glucose and glycated haemoglobin (HbAIc %) (p<0.001), triglyceride (p<0.01) and decrease in plasma high density lipoprotein cholesterol (p<0.05) in type 2 diabetic patients when compared with the corresponding control. Morisky score was significantly correlated with fasting plasma glucose (r=0.633 p<0.05) and HbAIc %( r=0.549, p<0.05). An association between FPG and HbAIc% and medication adherence rate of 66.7% was obtained for type II DM. Adherence to medication regimens showed a correlation with glycemic control (p<0.05). Self-reported Morisky medication adherence score could be used to predict the degree of haemoglobin glycation (HbA1c %) and therefore the risk of developing diabetic complications.
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