Furosemide terminates generalised seizure status epilepticus | 16725
International Research Journals
Reach Us +44 330 818 7254

International Research Journal of Pharmacy and Pharmacology

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Furosemide terminates generalised seizure status epilepticus in a woman with inter-ictal focal seizures


S. E. Oriaifo, Nicholas Oriaifo, E. K. I. Omogbai, F. Enahoro

tatus Epilepticus is an additional and life-threatening burden for patients living with epilepsy and their families. Extra precautionary measures attend the use of present medications available to treat the disorder. In this report, a 55-year old woman who presented with recurrent generalised tonic-clonic seizures and loss of consciousness between seizures had her attacks abated with 40mg of intravenously-administered furosemide. Her vital signs remained unperturbed and she regained consciousness in less than 30 minutes of the furosemide administration indicating that there was no evolution to subtle status epilepticus; after which there was post-ictal sleep which lasted about two hours. Also in this report, the mechanism of action of furosemide responsible for its seizure-terminating effects is discussed. The use of furosemide with its therapeutic efficacy, low cost and safety profile may stand to be a welcome addition to the armamentarium available to deal with status epilepticus.

Share this article