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Effect of different concentration of red palm olein on blood | 16787
International Research Journals

Effect of different concentration of red palm olein on blood lipid profile in rat.

Abstract

Eqbal M. A. Dauqan, Halimah Abdullah Sani, Aminah Abdullah and Zalifah Mohd Kasim

In this paper, we aimed to investigate the effect of different concentration of red palm olein (RPO) on blood lipid profile in rat. Seventy eight Sprague Dawley male rats were randomly divided into thirteen groups of 6 rats per group with 6 rats for T0 group which kill before any treatment. Treated groups were given with different concentrations of RPO (5%, 10% and 15%) for 2, 4 and 8 weeks. Rats in control group were given normal rat pellet only while in treated groups 5%, 10% and 15% of additional RPO were given. Results showed a decline in Low Density Lipoprotein Cholesterol (LDL-C) values whereas the High Density Lipoprotein Cholesterol (HDL-C) values increased. Rats treated with 15% RPO for 8 weeks showed an increased in the mean LDL-C level and decreased in HDL-C compared to the control group. At 2 and 4 weeks of treatment, the total cholesterol was no significant difference (pâ�?¥0.05) between control group and groups fed with different concentration (5%, 10%, and 15%) RPO but At 8 weeks, the total cholesterol level decreases in all concentrations compared to control group. The results of triglyceride (TG) in all treated rats were within the normal range. There was no significant difference (pâ�?¥0.05) in TG of rats treated with RPO compared to the control group.

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