Centratherum anthelminticum attenuates carbon tetrachloride- | 71971
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Centratherum anthelminticum attenuates carbon tetrachloride-induced Liver injury through inhibition of oxidative stress in albino rats.


Sumera Rais

Liver is the main vigorous organ of the body and a main site for metabolism and excretion of various endogenous and exogenous materials. Liver disorder are the major task to the international public health. Because modern medicine has little to offer for the treatment of liver diseases and sometimes have a side effect. The development of safe hepatoprotective agents remains an unmet need. Therefore, we investigated the Antioxidant and hepatoprotective effects of Ethanolic (ESEt) and hexane soluble fraction (HSF) of C. anthelminticum seeds (black cumin) against the carbon tetrachloride-induced hepatotoxicity in albino rats. The test doses of ESEt (600 & 800mg) and HSF (800mg) were effective by preventing the elevated levels of Serum alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), gamma glutamyl transaminase (GGT) in their respective test groups

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