Alterations of immunoglobulin expressions in newly diagnosed mycobacterium tuberculosis infected patients attending General Hospital Owerri

Abstract

Opara Ambrose Uche

The serum immunoglobulin (IgA, IgG, IgM) levels of Tuberculosis patients attending General Hospital Owerri, Nigeria were determined. Forty five confirmed Tuberculosis patients 20–60 years were selected. Forty five normal subjects age 20–60 years were used as control. The levels of immunoglobulin (IgA and IgG) were significantly increased in tuberculosis (p<0.05), except immunoglobulin M, that was not significantly increased, when compared with the control. The result suggests, that increase in immunoglobulin (IgA and IgG) indicates that tuberculosis may be interpreted as humoral response to mycobacterial antigens.

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