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Author(s): Srishti Bhannot*
A fertilized mouse egg and a fertilized human egg are similar in size, yet they produce animals of very different sizes. What factors in the control of cell behaviour in humans and mice are responsible for these size differences? The same fundamental question can be asked for each organ and tissue in an animal's body. What factors in the control of cell behaviour explain the length of an elephant's trunk or the size of its brain or its liver? These questions are largely unanswered, at least in part because they have received relatively little attention compared with other questions in cell and developmental biology (Navarrete et al., 2017). It is nevertheless possible to say what the ingredients of an answer must be. The size of an organ or organism depends mainly on its total cell mass, which depends on both the total number of cells and the size of the cells. Cell number, in.. View More»
DOI:
10.14303/2141-5153.2022.29