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International Research Journals

International Research Journal of Biochemistry and Bioinformatics

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Sandra M Blois

University Medical Center Hamburg- Eppendorf (UKE), Germany

Publications

  • Short Communication   

    Author(s): Sandra M Blois*

    A healthy placenta has long been acknowledged during gestation as a keystone of fetal development, and nearly all pregnancy complications have been linked to improper development of the placental vasculature. Restriction of placental blood flow has major consequences for both fetus and mother during gestation. Increased vascular resistance and reduced uterine blood flow are associated with intrauterine growth restriction, and are predictors of high-risk pregnancies. On the maternal side, the demand for increased blood flow in an improperly formed placenta has dangerous consequences for maternal health, leading to pregnancy diseases such as preeclampsia. The galectin (gal) family, defined by a canonical carbohydrate recognition domain (CRD) of approximately 130 amino acids with specificity for ?-galactosides, represents the most widely expressed class of lectins in all orga.. View More»

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