Research Article
Characterization of Withania somnifera (L.) Dunal silver nanoparticles and its antimicrobial effect on biofilm forming pathogenic microbes
Author(s): Logeswari. N and Prabhakaran. S.G.*
Withania somnifera (L.) Dunal (Solanaceae), commonly known as ashwagandha or Indian ginseng is a valuable medicinal plant and it is very potent, far and wide used herb in Ayurveda and other traditional systems of medicine in India. The qualitative and quantitative analysis has shown that methanol, ethanol and isopropanol has rendered a good yield of secondary metabolites. The silver nanoparticles used in W. somnifera AgNPs were characterized using UV-VIS spectrophotometry has shown two characteristic absorbance peaks value at 261.46 nm and 451.67 nm. The W. somnifera AgNPs has been detected with considerable antibacterial effect in comparison with the crude extract. The scanning electron microscopic (SEM) analysis also reveals the influence of W. somnifera AgNPs over the inhibition of biofilm formation in test pathogen Pseudomonas. The present study shows that isopropanolic root extra.. View More»
DOI:
http:/dx.doi.org/10.14303/irjps.2022.013