Okesola, Abiola Olukemi and Olola, Aderonke Funmilayo
Pseudomonas aeruginosa is an important opportunistic pathogen, and one of the leading causes of nosocomial infections especially in immunocompromised patients. Disinfection is one of the basic components of any infection control program, but the constant use of some disinfectants has led to the development of resistance among some nosocomial organisms such as P.aeruginosa, and a cross resistance to antibiotics. This study was conducted to evaluate the activities of 3 commonly used hospital disinfectants on P.aeruginosa at the University College Hospital, Ibadan,Nigeria. Fifty-five clinical isolates of P.aeruginosa were subjected to the 3 commonly used disinfectants namely jik, izal and dettol at different concentrations including the use-concentration of 10% by disc diffusion, MIC and MBC methods.The susceptibility of P.aeruginosa to the 3 disinfectants were found to be concentrationdependent. At the use–concentration of 10%, P.aeruginosa demonstrated good susceptibility to only izal while susceptibilities to Jik and dettol were intermediate and resistant. The highest activity of these disinfectants against P.aeruginosa was recorded in izal while the lowest activity was recorded in dettol. Based on the results of this study, izal can be effectively used in U.C.H. as a disinfectant while dettol and Jik are either discarded or the use–concentration increased.
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