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Surgical pathologic review of appendectomy at a sub-urban tropical tertiary hospital in Africa| Abstract

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Surgical pathologic review of appendectomy at a sub-urban tropical tertiary hospital in Africa

Abstract

Abudu Emmanuel Kunle, Oyebadeyo Tope Yinka, Tade Adedayo Oluyomi, Awolola Nicholas Awodele

Acute appendicitis is a popular cause of acute surgical abdomen worldwide. This study is further aimed at discovering any unusual pathology of the appendix that was not entertained clinically. To determine the clinical and histological characteristics of all the appendicectomy samples received in the Department of Morbid Anatomy and Histopathology of Olabisi Onabanjo University Teaching Hospital, Sagamu, South West Nigeria. A review of the medical and pathological records including slides of appendicectomy samples received between January 2002 and December 2010 was done. Routine haematoxylin and eosin (H&E) staining were carried out. A total number of 163 appendicectomy specimens were received. The mean age of the patients was 26.7 years, modal age was 35 years (range - 9months to 80years). Male to female ratio was 1.2: 1. Fourteen cases had normal histologic findings, giving a negative appendicectomy rate of 8.6%. Of the 149 appendices with pathology, only 130 cases (87.2%) showed histologic evidence of acute appendicitis with an average annual frequency of 14.4, 4 (2.7%) cases were chronic appendicitis, 10 (6.7%) cases showed reactive lymphoid hyperplasia; while 5 cases (3.4%) had submucosal fibrosis. Thirty seven cases (22.7%) had both gross and histological evidences of perforation. Fifty - nine cases (36.2%) had histological evidence of peritonitis. Although, incidence of acute appendicitis is low in Sagamu, South West Nigeria, patients however, presented lately with fairly high rates of perforation and post appendectomy wound infections.

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