Pharmacodynamics (PD) examines the biochemical and physiological effects of drugs, as well as the mechanisms by which they exert therapeutic or toxic actions. It complements pharmacokinetics by focusing not on what the body does to the drug, but on what the drug does to the body. Core PD concepts include receptor binding, dose?response relationships, and the therapeutic index. PD insights are crucial in drug discovery, clinical practice, and adverse event management. By understanding the molecular targets of drugs, researchers can develop more selective agents with fewer side effects.
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