+44 3308180992Meera Venkatesan
Drug interactions and polypharmacy have become increasingly important issues in clinical practice due to the aging population and the prevalence of chronic diseases requiring multiple medications. Polypharmacy, commonly defined as the concurrent use of five or more drugs, can increase therapeutic complexity, risk of adverse drug reactions (ADRs), and the likelihood of drug–drug interactions (DDIs). While some drug combinations are necessary for effective disease management, inappropriate polypharmacy can compromise patient safety. Recognizing and managing drug interactions requires an understanding of pharmacokinetics, pharmacodynamics, and patient-specific factors. Pharmacists and clinicians play a pivotal role in mitigating risks while optimizing therapeutic outcomes.
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