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International Research Journal of Biotechnology

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Current Diagnostics Strategies for COVID-19

Abstract

Moges Demes*, Nega Berhane

Novel COVID-19 caused by Sever Acute Respiratory Syndrome (SARS-CoV-2), was first seen at the end of 2019, in Wuhan, China. It is still causing major loss of human life and economic crisis in almost all countries around the world. Coronavirus have different families and orders. Early detection, isolation, and diagnosis of COVID-19 patients are checked early by quick, sensitive, and accurate identification techniques. Currently, a lot of research and investigations across the world are being done to discover efficient diagnostic techniques to combat the COVID-19 pandemic. Several diagnostic tests such as real-time-polymerase chain reaction, isothermal Loop-Mediated Amplification (LAMP), genome sequencing, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technique and microarray based assays etc. are currently available for diagnosis of COVID-19 infection. This review gives a brief overview of promising current COVID-19 diagnostic techniques used for the detection of SARS-CoV-2 and discusses their advantages and limitations with the aim of providing a reference for rapid and accurate diagnosis of COVID-19.

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