Motor Neuron Disease (MND) is a devastating neurodegenerative disease with a poor prognosis and severe disability. Many potential external risk factors have been proposed as part of a gene-environment interaction in the etiology of MND. This result is also supported by current hypotheses concerning the cellular and genetic origins of MND. A motor neuronopathy that exacerbate Fronto Temporal Dementia is known as MND (FTD). Frontal and temporal neocortical atrophy induce severe personality changes, inappropriate social conduct, and executive difficulties in people with FTD. Motor neuron disease causes symptoms such as bulbar palsy and limb amyotrophy. Frontal executive function deficits are seen in MND/Amyotrophic Lateral Sclerosis (ALS) patients who are not considered demented. Furthermore, MRI has revealed anomalies in the frontal lobe. MND, according to Ayurveda, are caused by Vata Dosha. Vata oversees the nervous system's autonomic, peripheral, and central functions. It oversees the brain's cognitive and neurological processes. This article gives the information about the Ayurveda in management of MND, Panchakarma treatments for MND, various herbs and herbal formulations like Ashwagndha, Brahmi, Gotu kola, Shilajit, Kapakacchu, Medhya churna used in the treatment and management of MND.
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