GET THE APP

A possible protective role of glucose-6-phosphate dehydrogenase deficiency and sickle haemoglobin genes against severe malaria in Madonna University, Elele Community| Abstract

süperbetin

A possible protective role of glucose-6-phosphate dehydrogenase deficiency and sickle haemoglobin genes against severe malaria in Madonna University, Elele Community

Abstract

Francis M. Awah, Nwanedo Chukwuemeka G., Salami Ibrahim Olalekan, Augusta Ehijie Azeke, Mbaike Nneka

The high frequency of the enzymopathy, glucose-6-pho sphate dehydrogenase (G6PD) deficiency and haemoglobinopathy, sickle cell haemoglobin (HbS) in malaria endemic regions is believed to be due to a heterozygous advantage against severe malaria. How ever, data to prospectively confirm the selective protection in different regions are lacking. In thi s study, the frequency of these genetic defects, th eir extent of interaction and contribution to severe ma laria protection was investigated in Madonna University community. The methaemoglobin method was used to determine the G6PD status while haemoglobin genotype was determined using cellulose acetate paper electrophoresis with Tris-EDTA- borate buffer (pH 8.9)

Share this article

tempobet

tempobet girişbursa escort

tempobet giriş

tempobet giriş linki tipobet e yeni giriş tipobet e yeni giriş tipobet son giriş süpertotobet güncel