+44 330 818 7254 Research Article
GCMS ANALYSIS AND MOLECULAR DOCKING STUDIES OF BIOACTIVE COMPOUNDS IN LEAF EXTRACT OF Syzygium samarangense
Author(s): Alwin Philip*, Nivetha L and Deepa Rajan
The study focuses on the results of docking studies conducted on Staphylococcus aureus, a pathogenic bacterium
responsible for causing various infections in humans. The study utilized GC-MS analysis of methanol extract
of Syzygium samarangense leaf to identify potential inhibitors of specific enzymes in the organism, which are
essential for its survival and virulence. The docking studies involved the virtual screening of several molecules
against 4 target proteins of Staphylococcus aureus and the results were analyzed using molecular visualization and
scoring tools. The study identified several compounds that showed high binding affinities to the target proteins,
indicating their potential as effective inhibitors. The findings of this study provide valuable insights into the
design of novel and potent inhibitors against Staphylococcus aureus, which could help in the development of.. View More»
DOI:
10.14303/2141-5153.2023.60