A series of actions that result in the entry of the virus into the cell are triggered when the viral particle interacts with its cellular receptor on the surface of the host cell. The type of cellular receptor expressed on the cell surface plays a specific role in the contact and subsequent attachment of the virus with the host cell. In this approach, viruses selectively infect particular cell types, species, or groups of organisms. In other circumstances, various co-receptors or even chemicals created as a result of signal transduction are necessary, although a cellular receptor can alone mediate viral entry into the host cell. Here, we examine the cellular receptors of a few viruses with significant medical relevance and their roles in viral infection (Alkhatib 2009).
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