Sero-epidemiological study of Human African Trypanosomiasis | 18170
International Research Journals

Sero-epidemiological study of Human African Trypanosomiasis in non-endemic areas


Atif Elamin Abdelgadir, Khalil Mohammed Khalil , Mubarak Abdel Rahman, Khitma Hassan Elmalik, Intisar El Rayah

Human African Trypanosomiasis surveys were conducted using Card Agglutination Test for Trypanosomiasis (CATT) in displaced people’s camps and prisoners in Khartoum state, who originated from endemic areas in southern Sudan, the result showed that 60 out of 211 cases and 38 out of 144 cases were positive (28.4% and 26.4%, respectively), however Parasitological examination did not show any parasite. A comparison between CATT and Card Indirect-Agglutination Antigen Test for Trypanosomiasis (CIATT) for the diagnosis of sleeping sickness was done on 250 serum samples the result indicated that 71 positive cases (28.4%) for CATT and only 15 positive cases (6%) for CIATT. CATT and CIATT were found similar in their cross reactivity which resulted in the detection of the false positive cases of sleeping sickness from patients with malaria and leishmaniasis from non-endemic areas of sleeping sickness (46% and 42.9% detected by CATT, respectively) and (28% and 34.3% detected by CIATT, respectively).

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