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Relationship between sex hormones in patients with infertility and air pollution.| Abstract

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Relationship between sex hormones in patients with infertility and air pollution.

Abstract

Silva, O.R., Azzalis, L.A., Braga, A.L.F., Martins, L.C.A., Junqueira, V.B.C.; Fonseca F.L.A.

Recent studies have linked exposure to pollutants with disruptive action on the endocrine system and problems such as infertility, reduced male fertility, abnormal sexual development, among others. Due to extensive evidence indicating that human health may suffer adverse consequences from exposure to pollutants that interact with the endocrine system, this study investigated the effects of pollutants on sex hormone tests from male and female patients who were assisted by reproduction clinic of the specialties of the Faculty of Medicine of ABC. This quantitative, retrospective, descriptive crosssectional study was done with data obtained from the records of Ambulatory Specialty of the Faculty of Medicine of ABC. Hormone tests such as follicle stimulating hormone (FSH), luteinizing hormone (LH), estrogen, progesterone, testosterone and prolactin were performed and they were evaluated with data of the pollutants: carbon monoxide (CO), ozone (O3), sulfur dioxide (SO2), nitrogen dioxide (NO2) and particulate matter < 10 µg/m3 (PM10). Our results suggest that PM10 was responsible for the observed changes in the hormone prolactin, corroborating the concept that air pollution can have a disruptive action on human reproductive health.

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