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Moringa oleifera diet improves the toxic effects of palm win | 16740
International Research Journals

Moringa oleifera diet improves the toxic effects of palm wine and local gin on hematological and hemostatic parameters in albino rats

Abstract

Okwari Obem Obo, Kolawole Tolunigba Abisola, Wali Catherine, Oluwatayo Beatrice Olatundun, Okon Hannah

The effect of Moringa oleifera diet on the toxic effects of palm wine and local gin on hematological and hemostatic parameters in albino rats was determined in this research. Thirty female albino wistar rats were used for this study. The rats were aged 8 to10 weeks and weighed between 170g and 200g. They were divided into six groups: Groups 1 to 6 of 5 rats each. All the rats except the ones in group 1 were fed with 11.1% of Moringa oleifera diet. Group 1 served as the Control group; rats in this group were given normal rat chow, group 2 rats were given Moringa oleifera diet only , g roup 3 rats were given 10 ml/kg bwt of palm wine only, group 4 rats were gi ven 0.03ml/kg bwt of local gin only, group 5rats were given 10ml/kg bwt palm wine with Moringa oleifera diet and group 6 rats were given 0.03ml/kg bwt of local gin with Moringa oleifera diet. Palm wine and local gin were administered to the rats daily using an oral cannula. All administrations were done for a total of 30 days. On the 31 st day, the rats were sacrificed and blood was collected through cardiac puncture for the determination of some hematological and hemostatic parameters. The results of this study showed that M.oleifera diet improved the hematological and hemostatic parameters of the rats that were adversely affected by palm wine and local gin.

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