Histopathological analysis of salivary gland biopsies in Kum | 16250
International Research Journals

Histopathological analysis of salivary gland biopsies in Kumasi: An 8 year retrospective study


Titiloye NA, Duduyemi BM, Okai I, Ossei PPS

The salivary gland shows wide spectrum of findings on histological examination when they are removed at surgery. The findings range from normal to malignant. The major salivary glands include parotid, submaxillary and sublingual while the othe rs found in many other locations in the head and neck region constitute the minor salivary glands. A ll cases of salivary gland tissues received at our department of Pathology between the year 2009 and 2 016 were selected for this study. Data regarding histological diagnosis, age, sex and location were abstracted. The slides for the cases were retrieved from our archive and the histological diagnoses wer e revaluated. In cases where the slides were not found, the blocks were retrieved and new sections w ere cut for histological appraisal. The data obtained were uploaded into excel sheet and descrip tive analysis was carried out using SPSS version 23. Results obtained were presented in tables and c harts. 371 cases of salivary gland specimens were received during the 8 year period with M:F ratio of 1:1.22 average 46 cases per year. Most of the case s were from the major salivary glands with the most c ommon site being parotid gland (52%). The histology showed benign 167 cases (45%), primary ma lignant 103 cases (27.8%), inflammatory and tumour-like 86 cases (23.2%) while 4 cases (1.1%) w ere metastatic and 11 cases (2.9%) were normal. In the present study, most of our salivary gland biops ies were salivary gland tumours of which benign tumours are much more common than the malignant one s. Pleomorphic adenoma and non-Hodgkin lymphomas were the most common histologic types for the benign and malignant neoplasms respectively

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