Clinical Outcomes of Different Calcified Culprit Plaques in | 90097
International Research Journals

Clinical Outcomes of Different Calcified Culprit Plaques in Patients with Acute Coronary Syndrome


Mohammad Khalid Parvez*

Background: Previous research have observed that coronary artery calcification is carefully related to the prevalence of important unfavorable cardiac events (MACE). This take a look at aimed to research the traits and scientific consequences of various calcified plaques in sufferers with acute coronary syndrome (ACS) with the aid of using the use of optical coherence tomography (OCT).

Methods: 258 ACS sufferers with calcified offender plaques who underwent OCT-guided stent implantation have been enrolled. They have been divided into 3 subtypes primarily based totally at the calcified plaque morphology, along with eruptive calcified nodules, calcified protrusion, and superficial calcific sheet. Compared with superficial calcific sheet and calcified protrusion, eruptive calcified nodules had the finest calcium burden and a better price of stent aspect dissection (p < 0.001) and incomplete stent apposition (p < 0.001). In an average follow-up duration of two years, 39 (15.1%) sufferers skilled MACE (a composite occasion of cardiac death, goal-vessel myocardial infarction, ischemia-pushed revascularization), with a considerably better prevalence with inside the eruptive calcified nodules group (32.1% vs. 10.1% vs. 13.0%, p = 0.001). A multivariate Cox evaluation tested that the eruptive calcified nodules (threat ratio 3.14; 95% self belief interval, 1.64–6.02; p = 0.001) have been an impartial predictor of MACE.

Conclusions: MACE befell extra often in ACS sufferers with eruptive calcified nodules, and the eruptive calcified nodules have been an impartial predictor of MACE.

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