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International Research Journals

Abstract

Fatou Cisse*, Tarik Lamkinsi, Souleymane Thiam, Arame Ndiaye, Abdourahmane Samba, Najah Fatou Coly, Fatou Diallo-Agne, Alassane Diatta and Niama Diop S

Background: Metabolic syndrome (MS) is a real public health problem in our regions. Its severity requires early detection strategies based on clinical, anthropometric and biological criteria to ensure adequate management of this condition. Hyperuricemia, although not part of these criteria, is frequently associated with MS components. Thus, we have set ourselves the goal of finding a relationship between uric acid and MS. Methodology: We conducted a prospective study on 441 subjects received as part of an annual medical visit. The subjects included in the study benefited from a complete clinical examination and blood tests provided by this annual medical check (including blood sugar, lipid status, and uric acid). The biochemical parameters were determined using enzymatic methods adapted to the A15 automaton. The metabolic syndrome has been defined according to the criteria of NCEP-ATP III. Results: The prevalences of metabolic syndrome and hyperuricemia were 6.57% and 6.34%, respectively. Hyperuricemia was strongly associated with MS (OR=3.87, p=0.007) and some of these components including hypoHDlemia (OR=5.09), hypertriglyceridemia (OR=3.05), and abdominal obesity (OR=2.52). Conclusion: The positive association between hyperuricemia and MS demonstrates the interest of dosing uric acid in subjects at risk.

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