Antimicrobial sensitivity patterns of urine isolates from a | 17212
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International Research Journal of Microbiology

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Antimicrobial sensitivity patterns of urine isolates from a large Ghanaian hospital


Odonkor ST*, T. Mahami T and Addo KK

Monitoring antimicrobial susceptibility patterns of pathogens that cause Urinary Tract Infection is important to provide information concerning rising problems of antibiotic resistance and assistance in managing empirical therapy. The purpose of this study was to investigate the most prevalent pathogen in urine and evaluate its susceptibility and resistance using standard microbiological procedures. Urine culture and sensitivity results were compiled and analyzed from laboratory record books of a large Ghanaian hospital from 2009 to 2010. Within this period, a total of 3774 pathogens were isolated comprising 3510 bacteria and 264 yeast isolate. The most prevalent isolated pathogens were Escherichia coli (25.5%), Klebsiella (19.2%) and Staphylococcus aureus (18.6%). Other isolates included other Coliform spp(9.4%), Streptococcus sp (8.2%), Pseudomonas (7.1%), Candida alibicans (7%) and Proteus spp (4.9%). Only 9.3, 9.5 and 6.4% of E.coli was susceptible to Ampicillin, Pipemedic acid and Cotrimoxazole respectively. Susceptibility of E.coli to Nitrofuranton and Cefuroxime was 18.5 and 18.3% respectively. Susceptibility to Gentamycin, Tetracycline, and Nalidixic acid, were 15.4, 11.4 and 11.1% respectively.

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