The present study aimed to identify the effect of Carissa roots on its antibacterial potential. Six medically important bacterial strains were selected to identify the antibacterial potential by measuring their zone of inhibitions using agar well diffusion method. Antimicrobial activity of roots has been evaluated against various diseases causing organisms (Escherichia coli, Salmonella typhi, Staphylococcus aureus, Agrobacterium tumefaciens, Erwinia carotovora, Entarococcus faecalis) has shown positive activity against some of the tested extracts. Ethanol and methanol extracts of roots of all the four species have shown very promising activity againt Escherichia coli and Entarococcus faecalis. For ethanol extract the Carissa carandas L. has shown the highest activity against Escherichia coli and Carissa congesta Wight and Carissa spinarum L. has shown the highest activity against Entarococcus faecalis. In methanol extract Carissa carandas L. and Carissa opaca Stapf ex Haines have shown very promising activity againt Staphylococcus aureus. Thus, the study proves significant difference between the antibacterial activities of roots of Carissa species.
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