International Research Journal of Basic and Clinical Studies Vol. 4(2) pp. 014-017, December 2016
Copyright©2016 International Research Journals


Full Length Research Paper

Sero-prevalence of Hepatitis B and Hepatitis C virus infection among Sudanese blood donors

AbdelSalam MH Elfaki1*, Mohamed A Agab1, Eldisugi H M Humida1, Khalid ME Eltalib2, Yasir DH Elbedri2 and AbdelAzeem HH Hamed2

1Department of Medicine, Faculty of Medicine, University of Kordofan, Sudan

2Department of Medicine, Elobeid Teaching Hospital, Ministry of Health, Sudan

*Corresponding author email address: elfakioo9@


Infection with hepatitis B and hepatitis C virus causes serious mortality, morbidity, and financialburden and therefore they constitute a major global health problem. This study was conducted todetermine the sero-prevalence of hepatitis B and hepatitis C infection among healthy volunteer blooddonors at Elobeid blood bank. This cross-sectional study was conducted among male Sudanesevoluntary blood donors at the blood bank of Elobeid teaching hospital in the period June 2014 toAugust 2014. A total of 400 blood donors were included in the study. Blood sample was taken fromeach individual tested for evidence of hepatitis B and hepatitis C infection markers using immunechromatographic(ICT) strips. Data sheet for collection of personal data (such as name, age, and sex)and socioeconomic data (such as marital status, education and occupation), history of immunizationagainst hepatitis B, history of tattooing, was prepared and used for each individual. Data wereanalyzed using Statistical Package for the Social Sciences (SPSS) version 18.0 This cross-sectionalstudy includes 400 apparent healthy blood donors who came consequently for blood donation. Allparticipants were males. The age of the donors ranged from 18-48 years with a mean of 28.5 (SD ± 6.3)years. Majority of the donors were in the groups 18-27 years (49.75%) and age group 28- 37 years(41.5%). These two age groups constitute 91% of the donors. The overall sero-prevalence of hepatitis Bvirus and hepatitis C virus infection among blood donors was 9.3%, and 3.5% respectively. The meanage of those with hepatitis B virus infection was 29.8 (SD ± 4.7) years and the mean age of those withhepatitis C virus infection was 34 (SD ± 6.6) years. More than half (57%) of those have sero-positivemarkers of hepatitis B and hepatitis C infection, belong to the age group 28-37 years. The majority ofindividuals (86%), who are positive for hepatitis C antibodies, came from urban, while those withpositive HBsAg coming from urban constitute 59%. The level of education of two third (74.3%) of blooddonors included in this study was basic or secondary level. More than half (59%) of individuals withHBsAg are workers, while workers and merchants are equally affected with hepatitis C infection andtogether they constitute 86% of cases with positive antibodies against hepatitis C. This study showsthat the sero-prevalence of hepatitis B is high and sero-prevalence of hepatitis C is rising amongapparent healthy blood donors. To reduce the prevalence of hepatitis B infection, it will be necessaryto educate people about risks factors for infection and benefits of immunization. In the absence ofhepatitis c vaccine, proper screening of blood and selection of donors will have a paramountimportance to ensure a safe blood supply.

Keywords: Sero-prevalence, blood donors, hepatitis B virus, hepatitis C virus