|International Research Journal of Pharmacy and Pharmacology Vol. 3(4), pp. 41-45, April 2013
Copyright © 2013 International Research Journals
Full Length Research paper
Preliminary result on the immediate hypoglycemic effect of “JAMU” extract “JAMSI” on hyperglycemic volunteers
*1Ning Harmanto, 2Prapti Utami and 3Willie Japaries
*1PT Mahkotadewa Indonesia
2CV Sekar Utami Toga, Indonesia
3Head of Sinshe Competence Certification Board, Indonesia
*Corresponding Author E-mail: firstname.lastname@example.org
Received March 18, 2013; Accepted April 17, 2013
The article studies the immediate hypoglycemic effect of “jamu” herbal extract JAMSI (produced by PT Mahkotadewa Indonesia; registered at Indonesian Food and Drugs Authority: TR053649111) among hyperglycemic volunteers. This study was designed as a pre and post treatment’s effect evaluation among hyperglycemic volunteers. Volunteers were recruited from visitors to the “jamu” shop during the study, who were hyperglycemic and ready to be tested with the “jamu” remedy under study. Their blood sugar were tested using glucometer Accu-Chek Active (made in Germany) before and one hour after consuming the “jamu” under study ie. JAMSI. The paired blood sugar data were analyzed using student-t test with paired samples, one sided, with significance cut off point α=0,05. During two study days on 16th and 23rd February 2013 in Jakarta, there were 34 volunteers eligible to the study. They consisted of 20 female and 14 male, 20 volunteers were still consuming western hypoglycemic medicine. Their age ranging from 22 to 74 years (52,26 ±10,10 years), with diabetes mellitus history ranging from 1 to 33 years (9,36±8,27 years). Their average capillary blood sugar level before consumption of the tested “jamu” remedy was 243,03±97,97 mg/dl and one hour after consumption of the remedy was 197,94±100,01 mg/dl. The difference was highly significant (P<0,01). Analysis upon those with initial blood sugar above 200mg/dl versus those with lower than 200mg/dl indicated that the reduction of blood sugar level was more prominent among those with higher initial blood sugar level (table 3). The hypoglycemic effect was not significantly differently (P>0,05) between those still consuming oral antidiabetic drugs and those not consuming oral antidiabetic drugs. The “jamu” remedy under study ie. “JAMSI” showed very significant immediate hypoglycemic effect and apparently free from serious utoward effects among the tested volunteers. More studies are required to assess the medium and long term effects of the “jamu” remedy.
Keywords: JAMU, antidiabetic, herbal extract, diabetes mellitus.