International Research Journal of Biochemistry and Bioinformatics

International Research Journal of Biochemistry and Bioinformatics (ISSN-2250-9941) Vol. 6(1) pp.007-010, December, 2016. DOI: http:/dx.doi.org/10.14303/irjbb.2016.112. Copyright © 2016 International Research Journals  

 

Full Length Research Paper

Descriptive analytical study of 41 colorectal cancer cases operated in Senegal

Arame Ndiaye1, Fatou Diallo1, Abdourahmane Samba1, Sekossounon Sanni1,  Fatou Cisse1, Dominique Doupa2, Souleymane Thiam1, Ndene Gaston Sarr1, Niama Diop Sall1, Meissa Toure1

1Laboratory of Biochemistry, Molecular Biology - Cheikh Anta Diop University of Dakar, Senegal

2Laboratory of Biochemistry, Molecular Biology -Training and Research Unit (UFR), Department of Health Gaston Berger University, Saint Louis, Senegal

Corresponding Author Email: yssndiay@yahoo.fr Tel: 00221-338244484

Received September 12, 2016;  Accepted November 15, 2016

Abstract               

 

In Senegal colorectal cancer cases account for 2.5% of all cancers. This prevalence is underestimated as due to the inaccessibility to care. The aim of our study was to describe anatomopathological and epidemiological characteristics in patients with colorectal cancer in Senegal. This is a prospective, descriptive and analytical study from 2012 to 2015 on patients having undergone surgery for colorectal cancer. 41 cases were selected on a more important number of filed cases. Data based on factors such as age, sex, tumor location, and diagnosis of stage (TNM) were studied using the Excel software. The average age of our patients was around 50 and the majority was above 60. The sex ratio was 0.76 for women. Our study population was dominated by the Wolof ethnic group, which accounted for over half of the targeted population (51%). Other ethnic groups were poorly represented. Adenocarcinoma histology was dominant, with preferential localization at the left colon. The stage of diagnosis according to the TNM classification was pT3. Our study shows that the majority of patients come to consultation at a somewhat advanced stage. Alongside this analytical study, a genetic study of DNA will be performed at the Laboratory of Biochemistry and Molecular Biology at the University Cheikh Anta Diop of Dakar.

 

Keywords: Colorectal Cancer, descriptive study, Senegal

 

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